PET/CT May Unmask Hidden Cancers in Li-Fraumeni Patients

By Charles Bankhead

BOSTON, March 20 -- Occult malignancies in patients with Li-Fraumeni syndrome have more difficulty hiding from whole-body fluorodeoxyglucose F18 (FDG) PET/CT imaging, results of a preliminary clinical evaluation suggest.

Imaging revealed asymptomatic malignancies in three of 15 patients with Li-Fraumeni syndrome and no history of cancer, Judy E. Garber, M.D., of Dana-Farber Cancer Institute here, and colleagues, reported in the March 19 issue of the Journal of the American Medical Association.

Identification of the malignancies at an early stage allowed all three patients to undergo potentially curative treatment.

source: Medpage Today

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