8.28.2008

More MRI and CT machines, more exams performed (Canada)

August 21, 2008—The supply of magnetic resonance imaging (MRI) and computed tomography (CT) scanners in Canada increased significantly over four years, according to a new report from the Canadian Institute for Health Information (CIHI). Medical Imaging in Canada, 2007 reports that in 2007, there were 419 CT scanners and 222 MRI machines installed and operational in Canada, up from 325 and 149, respectively, in 2003. In the most recent year, between 2006 and 2007, the number of CT scanners increased by 27 and the number of MRI scanners increased by 21. The rate of MRI and CT exams performed per 1,000 population in Canada rose by 43% and 28%, respectively, in the four years between 2003 and 2007, and rose by 4% and 5%, respectively, in the most recent year.

Despite the increases, Canada, with 12 CT scanners and 6 MRI machines per million population, falls below the Organisation for Economic Co-operation and Development (OECD) median of 15 CT scanners and 7 MRI machines per million population in 2005, the latest year for which data are available. There were 103 CT exams per 1,000 people performed in Canada in 2007, less than the rate performed in both the United States (207) and Belgium (138), but higher than the rate in Sweden (89), Spain (57), England (54) and Denmark (34). In comparison, Canada’s rate of MRI exams per 1,000 population (31) was higher than that in England (25), Spain (21) and Denmark (17), and lower than in the U.S. (89), Belgium (43) and Sweden (39).

source: Canadian Institute for Health Information

8.23.2008

Carnegie Mellon Scientists Develop MRI Technology That

PHILADELPHIA—Magnetic resonance imaging (MRI) isn't just for capturing detailed images of the body's anatomy. Thanks to novel imaging reagents and technology developed by Carnegie Mellon University scientist Eric Ahrens, MRI can be used to visualize — with "exquisite" specificity — cell populations of interest in the living body. The ability to non-invasively locate and track cells, such as immune cells, will greatly aid the study and treatment of cancer, inflammation, and autoimmune diseases, as well as provide a tool for advancing clinical translation of the emerging field of cellular regenerative medicine, by tracking stem cells for example.

Ahrens will present his research on this new approach, called fluorocarbon labeling, Thursday, Aug. 21 at the 236th national meeting of the American Chemical Society in Philadelphia.

"With our technology we can image specific cells in real-time with exquisite selectivity, which allows us to track their location and movement and to count the apparent number of cells present. We then use conventional MRI to obtain a high-resolution image that places the labeled cells in their anatomical context," said Ahrens, an associate professor of biological sciences at the Mellon College of Science.

source: Carnegie Mellon University

8.22.2008

Draeger Fabius MRI Receives FDA Clearance To Provide Advanced Anesthesia Technology In The MR Environment

Draeger Medical, Inc. announced that the Draeger Fabius MRI anesthesia machine has received FDA clearance. The newest member to the family of Draeger anesthesia machines is designed specifically to meet the requirements for the Magnetic Resonance Imaging (MRI) environment.

The Fabius MRI is designed for use with 1.5T and 3.0T MRI systems. An integrated Teslameter provides an acoustic alarm if the Fabius MRI is positioned within a field strength greater than 40mTesla (400 Gauss).

The Fabius MRI employs the same user interface as Draeger's Fabius GS, Fabius Tiro and Apollo machines, creating a uniform and consistent interface for the anesthesia provider wherever anesthesia is required. The size of the MRI system often requires the anesthesia provider to be outside the room or some distance away from the device during an examination. To accommodate this, additional optical alarm displays (LEDs) at the top of the system provide visual indication for all alarm conditions for the safety of the patient in this specialized environment.

source: Draeger

8.21.2008

Landmark Study Leads To Concern Over The Safety And Cleanliness Of MRIs

Peter Rothschild, M.D., renowned Radiologist and MRI expert, has released the ground-breaking paper, recently published on AuntMinnie.com, titled "Preventing Infection in MRI: Best Practices for Infection Control in and Around MRI Suites." This article expands on the issue that MRIs are often not being properly cleaned, thus leading to concern over Methicillin Resistant Staphylococcus Aureus (MRSA) spread during radiological scans, in particular MRI.

MRSA was originally identified in 1961 and is now widespread throughout healthcare facilities, both hospital and outpatient settings. The most common source for transmission of MRSA is by direct or indirect contact with people who have MRSA infections or are asymptomatic carriers.

source: Medical News Today

8.15.2008

GE Healthcare Recognizes First Magnetic Resonance Imaging System To Receive Ecomagination Certification

GE Healthcare, a unit of General Electric Company (NYSE: GE), announced its Signa HDe 1.5T Magnetic Resonance Imaging (MRI) system as the first medical imaging product from GE Healthcare to be recognized as an ecomagination offering after completing the company's rigorous internal environmental and operational evaluation, recognizing it as one of the most energy efficient 1.5T MRI systems commercially available.

Ecomagination is GE's commitment to imagine and build innovative technologies that help customers address their environmental and financial needs, such as the need for cleaner, more efficient sources of energy. The Signa HDe 1.5T was recognized as an ecomagination product on the basis of energy savings, as well as operating benefits. Compared to the average 1.5T MRI system, the GE Signa HDe 1.5T is designed to use over 20% less space, increasing siting flexibility.

source: GE Healthcare

MEDRAD Receives FDA 510(k) Clearance For Wireless MR Infusion System

MEDRAD, INC., announced that the wireless version of its Continuum MR Infusion System has received U.S. Food and Drug Administration (FDA) 510(k) clearance.

The new Continuum Wireless MR Infusion System enables the clinician to control a patient's medication infusion during a magnetic resonance (MR) procedure from both inside and outside the scan room. When changes are needed, including flow rate, bolus, or to start or stop the infusion altogether, clinicians can control these parameters without interrupting the MRI scan with a new wireless remote display featuring a color touch screen. This option will increase workflow efficiencies and throughput while enhancing clinician confidence by enabling easy selection from up to nine IV stands, minimizing scan interruptions due to infusion changes and displaying all infusion parameters.

source: Medical News Today

8.12.2008

GE Healthcare Recognizes First Magnetic Resonance Imaging System To Receive Ecomagination Certification

GE Healthcare, a unit of General Electric Company (NYSE: GE), announced its Signa HDe 1.5T Magnetic Resonance Imaging (MRI) system as the first medical imaging product from GE Healthcare to be recognized as an ecomagination offering after completing the company's rigorous internal environmental and operational evaluation, recognizing it as one of the most energy efficient 1.5T MRI systems commercially available.

Ecomagination is GE's commitment to imagine and build innovative technologies that help customers address their environmental and financial needs, such as the need for cleaner, more efficient sources of energy. The Signa HDe 1.5T was recognized as an ecomagination product on the basis of energy savings, as well as operating benefits. Compared to the average 1.5T MRI system, the GE Signa HDe 1.5T is designed to use over 20% less space, increasing siting flexibility.

source: GE Healthcare

7.28.2008

Conventional MRI And Computer Analysis Could Be Used To Detect Alzheimer's

Researchers using conventional, as opposed to high powered MRI equipment, and computer- based methods to analyze the scans, are breaking new ground in the diagnosis of the telltale signs of Alzheimer's Disease, increasing the likelihood that there will be reliable ways of diagnosing the disease non-invasively and before it is too late to do something about it.

Three studies, one on successful use of conventional MRI to image brain plaques in animals, and two on using computers to analyze MRI images, are being presented at the Alzheimer's Association's 2008 International Conference on Alzheimer's Disease (ICAD 2008), which is taking place in Chicago from 26th to 31st July.

source: Medical News Today

7.24.2008

Positive Phase I Safety Results for BFPET

FluoroPharma Inc., a company developing breakthrough molecular imaging agents for the Positron Emission Tomography (PET) market, announced positive Phase I results for BFPET, its novel Fluorine-18 labeled tracer for myocardial perfusion imaging.

BFPET is FluoroPharma’s second cardiovascular product to complete Phase I clinical development.BFPET is a PET imaging agent, designed to assess the blood flow in the heart (myocardial perfusion). Myocardial perfusion imaging is a standard test to assess coronary artery disease (CAD), with more than 9 million Americans undergoing the test annually. The Phase I trial, led by Principal Investigator Alan J. Fischman, MD, PhD at the Massachusetts General Hospital, was designed to evaluate safety, distribution and dosimetry of BFPET in 12 healthy subjects following a single dose injection at rest.

“BFPET Phase I data demonstrates that the agent has a favorable dosimetry and pharmacokinetics profile and is well tolerated. All safety endpoints were achieved with no adverse events and no clinically significant changes noted in follow-up clinical and laboratory testing”, said Dr. Fischman, Professor of Radiology at Harvard Medical School. “Biodistribution results indicate fast blood clearance, rapid and stable myocardial uptake and high heart to background ratios.”

source: Fluoropharma

7.20.2008

Heart Scan with Lower Dosage Possible Using Dual-Source CT

MALVERN, Pa., July 17, 2008 – A new study reveals that, with dual-source computed tomography (DSCT), the effective dosage for a heart examination can be significantly lowered, in comparison to conventional computed tomography. The study also demonstrated that stenoses can be diagnosed with similar high accuracy as with invasive X-ray angiography.

At the University Hospital Zürich in Switzerland, 120 patients with suspected coronary heart disease were scanned with the world’s first CT scanner with two X-ray tubes, a SOMATOM® Definition from Siemens Healthcare (www.siemens.com/healthcare). The Siemens application, Adaptive Cardio Sequence with the step-and-shoot mode, was also used for the first time with a dual-source CT. The results of the study were published in the June issue of Heart, the official journal of the British Cardiovascular Society.*

source: Siemens Healthcare

7.18.2008

Cost-Effectiveness Of 64-Slice CT Scanner In Emergency Department Chest Pain Patients Shown By Study

A recent study led by Rahul Khare, MD, emergency department physician and assistant director of operations at Northwestern Memorial Hospital, sought to determine the cost-effectiveness of utilizing a CT scanner to evaluate low-risk chest pain patients in the emergency room. The study results which are published in the July issue of Academic Emergency Medicine show that using a 64-slice CT scanner is more cost-effective than the current standard of care for evaluating and diagnosing this patient population, which includes an overnight stay in the observation unit and cardiac stress testing.

Chest pain is the most common emergency department complaint in patients 50 years and older, and has a variety of potential causes. A commonly missed and difficult to diagnose cause of chest pain is coronary artery disease. "When patients arrive at the emergency department with chest pain, my goal as an emergency physician is to identify any life threatening conditions and treat the patient promptly. Currently it is a challenge to identify chest pain patients with significant coronary artery disease in a timely and cost-effective manner," says Dr. Khare, who is also an Assistant Professor of Emergency Medicine at Northwestern University's Feinberg School of Medicine.

source: Medical News Today

7.14.2008

ACR's Guidelines For CT Colonography Interpretation Examined In Study At Digestive Disease Week

A study presented at Digestive Disease Week® 2008 examined the American College of Radiology's (ACR) CT colonography guidelines recommending that polyps ≤ 5mm in size not be reported on CT colonography by applying them to an endoscopic database that collected information about polyps that had been removed and processed. The guidelines also recommend that patients with one or two polyps 6 to 9 mm in size and no larger polyps can have repeat CT colonography in three years rather than prompt polypectomy. The database included information for 10,780 polyps removed from 5,079 patients (among 10,034 colonoscopies) over a five-year interval. Overall, the study determined that if CT colonography rather than colonoscopy had been used in this population, and assuming 100 percent sensitivity of CT colonography for polyps ≥ 6 mm and ACR interpretation recommendations, then 29 percent of all patients and 30 percent of patients over age 50 with high risk adenoma findings would have been interpreted as normal.

source: Medical News Today

7.09.2008

Portable Magnetic Resonance Imaging

Magnetic resonance imaging is one of the most important imaging methods used in medicine. However, MRI scanning has one major disadvantage: The machines are huge and extremely expensive, and almost impossible to transport.

The Magnetic Resonance working group at the Fraunhofer Institute for Biomedical Technology Engineering IBMT in Sankt Ingbert has made magnetic resonance imaging mobile. They collaborated with the New Zealand company Magritek to develop small portable devices. Dr. Frank Volke, head of the Magnetic Resonance working group, explains the core technology: "Instead of the large superconducting magnets that have to be cooled with liquid helium and nitrogen, extra-strong permanent magnets are installed in our devices. There is no need for cooling anymore." To make this possible, several permanent magnets are so arranged that the magnetic field lines overlap to form a homogeneous field. In this way, the developers have succeeded in developing small, less expensive, and above all portable magnetic resonance spectrometers that can even be powered by batteries.

source: Medical News Today

7.07.2008

UVA Physicist Wins International Award for Novel MRI Technique

CHARLOTTESVILLE, VA, June 30, 2008 - A researcher at the University of Virginia Health System, Chengbo Wang, Ph.D., assistant professor of Radiology, has received the prestigious W.S. Moore Young Investigator Award for Clinical Science from the International Society for Magnetic Resonance in Medicine (ISMRM). Wang was chosen for his research in developing a novel magnetic resonance imaging (MRI) technique that - for the first time ever - identified microscopic structural damages deep in the lungs of patients with asthma.

"The award committee received a record number of applications this year, and Dr. Wang's work stood out for its innovative approach and excellent presentation," says Dr. Vivian Lee, president of ISMRM.

source: University of Virginia Health System

7.03.2008

New Study Finds Coronary Arterial Calcium Scans Help Detect Overall Death Risk In The Elderly

Measuring calcium deposits in the heart's arteries can help predict overall death risk in American adults, even when they are elderly, according to a new study published in the July issue of Journal of the American College of Cardiology.

Matthew J. Budoff, M.D., one of the study's authors and a researcher at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed), said previous studies had found measuring coronary arterial calcium with computed tomography (CT) heart scans could predict overall death risks in most American adults.

source: Medical News Today

6.24.2008

Earlier Alzheimer's Diagnosis With Automated MRI Technique

An automated system for measuring brain tissue with magnetic resonance imaging (MRI) can help physicians more accurately diagnose Alzheimer's disease at an earlier stage according to a new study published in the July issue of the journal Radiology.

In Alzheimer's disease, nerve cell death and tissue loss cause all areas of the brain, especially the hippocampus region, to shrink. MRI with high spatial resolution allows radiologists to visualize subtle anatomic changes in the brain that signal atrophy, or shrinkage. But the standard practice for measuring brain tissue volume with MRI, called segmentation, is a complicated, lengthy process.

source: Medical News Today

6.22.2008

NIST/NIH Micromagnets Show Promise as Colorful ‘Smart Tags’ for Magnetic Resonance Imaging

BOULDER, Colo.—Customized microscopic magnets that might one day be injected into the body could add color to magnetic resonance imaging (MRI), while also potentially enhancing sensitivity and the amount of information provided by images, researchers at the National Institute of Standards and Technology (NIST) and National Institutes of Health (NIH) report. The new micromagnets also could act as “smart tags” identifying particular cells, tissues, or physiological conditions, for medical research or diagnostic purposes.

As described in the June 19 issue of Nature,* the NIST and NIH investigators have demonstrated the proof of principle for a new approach to MRI. Unlike the chemical solutions now used as image-enhancing contrast agents in MRI, the NIST/NIH micro-magnets rely on a precisely tunable feature—their physical shape—to adjust the radio-frequency (RF) signals used to create images. The RF signals then can be converted into a rainbow of optical colors by computer. Sets of different magnets designed to appear as different colors could, for example, be coated to attach to different cell types, such as cancerous versus normal. The cells then could be identified by tag color.

source: NIST News Release

6.21.2008

New MRI/Radiology Blindfold No Metal

Toms River, NJ - June 16, 2008 -- Terry Weber of Originals By Weber announces immediate availability of their new MRI Safe Blindfold examination mask; it is specifically designed with no metal parts for use during MRI and Radiology examinations of patients. The mask, made of disposable lightweight, non-toxic black foam with an adjustable elastic strap,(one size fits all) is comfortable to wear and low in cost. Mask can be used once and discarded or, with an optional Tissue Liner inserted between inside of mask and patient's face, basic mask can be re-used by many patients by simply replacing the used tissues with a new Tissue Pack (5-tissues in each pack). These Tissue Liners make the mask re-usable because they keep the inside of the mask always clean, fresh and sanitary. Another available option is Weber's new Washable Liner to keep inside of mask clean.

source: Conservative Voice

6.20.2008

iCAD Initiates Clinical Study of Its Virtual Colonoscopy CAD In Partnership With ACR Image Metrix

iCAD, Inc. (NASDAQ: ICAD), an industry-leading provider of Computer-Aided Detection (CAD) solutions for the early identification of cancer, today announced it has initiated a clinical study for Colon CAD, its virtual colonoscopy CAD product, in partnership with ACR Image Metrix, a subsidiary of the American College of Radiology (ACR). iCAD and ACR Image Metrix, having completed the development portion of the study, are collaborating on study execution including a multi-reader, multi-case (MRMC) clinical study designed to assess the impact of Colon CAD on the accuracy of interpreting CT Colonography exams also known as virtual colonoscopies. The study will also assess the sensitivity of Colon CAD for detecting polyps and will measure the impact of iCAD’s CT Colon CAD product on interpretation and workflow.

Virtual colonoscopy offers patients a less invasive option to conventional colonic polyp detection techniques. Reviewing these images can be tedious and challenging because of the amount of information captured in a CT exam. iCAD’s colon CAD product uses sophisticated image processing analysis technology to identify polyps in images with the potential for streamlining the reading process and improving accuracy, productivity and workflow.

source: iCAD Press release

6.19.2008

MIT Unlocks Mystery Behind Brain Imaging Star-Shaped Brain Cells Shown To Play Key Role

In work that solves a long-standing mystery in neuroscience, researchers at MIT's Picower Institute for Learning and Memory have shown for the first time that star-shaped brain cells called astrocytes-previously considered bit players by most neuroscientists-make noninvasive brain scans possible.

Imaging techniques such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) have transformed neuroscience, providing colorful maps of brain activity in living subjects. The scans' reds, oranges, yellows and blues represent changes in blood flow and volume triggered by neural activity. But until the MIT study, reported in the June 20 issue of Science, no one knew exactly why this worked.

source: Medical News Today

6.12.2008

CT Lung Cancer Screening No Cure-All For Smokers

Screening for lung cancer with computed tomography (CT) may help reduce lung cancer deaths in current and former smokers, but it won't protect them from other causes of death associated with smoking, according to a new study published in the July issue of the journal Radiology.

"Our study suggests that screening may be one way to reduce risk of death from lung cancer," said the study's lead author, Pamela McMahon, Ph.D., senior scientist at Massachusetts General Hospital and instructor in radiology at Harvard Medical School in Boston. "However, the number-one goal should still be to quit smoking, because it will reduce risk of death from many causes, including lung cancer."

MedicalNewsToday

6.09.2008

MRI Useful And Reliable In Surgical Planning Of Patients With Rectal Cancer

3T MRI can accurately stage, and help surgeons plan sphincter-sparing surgery in patients with rectal cancer, according to a recent study conducted by researchers at Qilu Hospital of Shandong University in Shandong, China.

"Recently, MRI has been increasingly accepted by radiologists, surgeons and patients to image the rectum because of its superior soft tissue contrast and multi-planar capability," said Chuanfu Li, MD, lead author of the study. "Most rectal MRI studies have used field strength of 1.5 Tesla or less. Only two recent studies focus on 3T MRI for diagnosing and staging rectal cancer. "No standard protocol is available for 3T MRI of the rectum, which may cause inconsistent diagnostic accuracy among institutions. The purpose of this study was to evaluate the image quality of various 3T MR sequences for preoperative staging and planning of sphincter sparing rectal cancer resection," he said.

source: American Roentgen Ray Society

6.06.2008

Korean FDA Approves the CereTom� Portable CT Scanner

DANVERS, Massachusetts & SEOUL, Korea- June 4, 2008—NeuroLogica Corporation and its Korean distribution partner, Dong Kang Medical Systems Co.,Ltd., announced that the CereTom(R) has received clearance from the Korean Food and Drug Administration (KFDA) for medical capital device imaging.

“We are thrilled that the CereTom has cleared Korean FDA,” said Eric M. Bailey, CEO and President of NeuroLogica Corporation. “South Korea is one of the most innovative and medically advanced countries in Asia, we are confident that the CereTom will improve the standard of care for critically ill patients with neurological emergencies. Our distribution partner, Dong Kang, Co. has an excellent reputation at the best medical institutions in South Korea. We are pleased that they will be representing the CereTom.”

source: NeuroLogica

6.05.2008

GE Healthcare Announces World's First High Definition CT Scanner

GE Healthcare, a global leader in imaging and in dose reduction technologies, has announced U.S. Food & Drug Administration (FDA) clearance of the LightSpeed CT750 HD, the world's first high definition CT scanner. LightSpeed CT750 HD will set the new standard for CT clarity, delivering the vision and the tools to allow clinicians to diagnose quickly and confidently.

At its heart is the first new detector material in 20 years; one that is, quite literally, a gem. GE engineers discovered that, by changing the molecular structure of real garnets, they could develop a scintillator capable of delivering images 100 times faster, with up to 33% greater detail through the body and up to 47% greater detail in the heart. They had unlocked the secret of the proprietary GE Gemstone Detector™, boasting the fastest primary speed in the CT industry, and the driving force of the first of its kind "Gemstone Spectral Imaging" process. Gemstone Spectral Imaging uses up to 2496 views per rotation (a 2.5x increase) to deliver improved spatial resolution and improved image quality across the entire field of view.

source: Medica News Today

6.04.2008

NOVA(R) Renal: A safe alternative to contrast enhanced MRA/MRI

CHICAGO, June 3 2008 – VasSol’s introduction of NOVA® Renal, a gadolinium-free procedure, offers a safe alternative to the standard contrast-enhanced Magnetic Resonance Angiography (MRA) and Magnetic Resonance Imaging (MRI) scans for patients suffering from renal disease. Contrast enhanced renal MRA/MRI has traditionally required the injection of a gadolinium based agent which the FDA has linked to the occurrence of a potentially life-threatening disease, Nephrogenic Systemic Fibrosis (NSF). NOVA® Renal provides a comprehensive evaluation of the renal arteries without contrast or ionizing radiation.

Who’s at Risk?
According to a report by the Centers for Disease Control (CDC), one in six individuals have kidney disease, threatening their renal function and putting them at greater risk when receiving a gadolinium-enhanced MRI scan.

source: VasSol

6.02.2008

Whole Milk is Effective and Cost-Effective as Oral Contrast Agent

An item commonly found in many homes – whole milk – is just as effective, costs less and is easier on the patient than a diluted (0.1%) barium suspension that is also commonly used as an oral contrast agent in conjunction with CT to examine the gastrointestinal tract, a new study finds.

The study included 215 patients undergoing abdominal and pelvic CT, said Chi Wan Koo, MD, lead author of the study. All patients were given an IV contrast media; 115 were also given whole milk as an oral contrast agent; 100 received a 0.1% barium suspension. Two radiologists reviewed all the images and scored them based on degree of bowel distension and bowel wall visibility. Adequate bowel distension is necessary to optimize resolution of the bowel wall and contents, said Dr. Koo.

The study found that the images taken of patients who were given whole milk were just as useful as the images that were taken of patients given the diluted barium, she said.

source: ARRS

6.01.2008

Cheaper Chest Pain Screening In Emergency Rooms Offered By New CT Technology

Eight million Americans visit U.S. emergency departments for chest pain each year. Although just five to 15 percent of them are found to be suffering from heart attacks or other cardiac diseases, more than half of these patients are admitted to the hospital for observation and further testing.

Computed tomography angiography (CTA), however, offers a way to more quickly and cost effectively identify patients at low-risk of cardiac problems like the blocked arteries that lead to heart attacks, according to the new University of Pennsylvania School of Medicine research. Penn experts will present research findings that could come to define new standards of emergency diagnostics and care at this week's annual meeting of the Society for Academic Emergency Medicine, the foremost professional society representing physicians who care for acutely ill and injured patients.

Medical News Today

5.31.2008

Cumulative radiation exposure shows increased cancer risk for emergency department patients

According to a new study, patients are receiving estimated doses of radiation from medical diagnostic imaging studies, such as CT (or CAT) scans, that may be detrimental to their long term health, putting them at an increased risk of developing cancer. To date, emergency physicians have not been made aware of the cumulative amount of radiation that their patients receive. In fact they currently have no way to know or estimate any given patients cumulative dose. A new study hopes to quantify and further explore these concerns.

Led by Timothy B. Bullard, M.D., M.B.A of the Orlando Regional Medical Center (ORMC), the cross-sectional study examined the amount of ionizing radiation that a random selection of patients received over a five-year period at ORMC and Washington Hospital Center in Washington, D.C. The study is the first to estimate the total cumulative radiation dosage delivered to a population from multiple diagnostic imaging modalities during a defined period of time.

source:Genetic Engineering and Biotechnology News